Abstract
This study aimed to examine the effect of catfish oil intervention enriched with omega 3 on lipid profiles and ox-LDL levels in the elderly. The research design used a randomized-controlled trial (RCT) in a single blind. Subjects were divided into three groups, the first group was given soybean oil (SO), second group was given catfish oil (CO), while the third group was given catfish oil enriched with omega 3 (CO+omega 3). The lipid profile and ox-LDL measurement was performed before and after the intervention. The results showed that CO+omega 3 group had significant reduction in total cholesterol. Triglyceride levels in CO and CO+omega 3 groups decreased after intervention, while triglyceride levels in SO goups increased, but no significant differences (p>0,05). The HDL levels increased in SO and CO groups, while CO+omega 3 decreased slightly, but did not different significantly (p> 0,05). LDL levels decreased in all groups, but the highest decrease was in the CO+omega 3 group. The ANOVA test showed that delta LDL levels in each treatment group did not different significantly. The ox-LDL level in each treatment decreased, but it was significant only in the treatment of catfish oil enriched with omega 3. Therefore, catfish oil enriched with omega 3 was chosen as the best intervention in improving lipid profiles and oxidative stress of the elderly.